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RStudio graphical illustrations of pca variable loading plots generated in
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
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GraphPad Software Inc graphic illustrations
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
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KAUST Core Labs graphic illustrator
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
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RStudio graphic illustrations
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustrations, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DeLano Scientific graphic illustrations
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustrations, supplied by DeLano Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Human Kinetics Inc graphic illustration
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustration, supplied by Human Kinetics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Verlag GmbH graphic illustration
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustration, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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SCHOTT graphic illustrations
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustrations, supplied by SCHOTT, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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MBL Life science illustration of organoid in the graphical abstract
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Illustration Of Organoid In The Graphical Abstract, supplied by MBL Life science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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OriginLab corp graphical illustration software origin
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphical Illustration Software Origin, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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GeneGo Inc graphic illustration
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustration, supplied by GeneGo Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Simio LLC graphic illustrations
Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) <t>PCA</t> of high and low IDO unstimulated (Unstim) MSC groups. (D) <t>PCA</t> <t>variable</t> plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).
Graphic Illustrations, supplied by Simio LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) PCA of high and low IDO unstimulated (Unstim) MSC groups. (D) PCA variable plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).

Journal: Cytotherapy

Article Title: Characterizing human mesenchymal stromal cells’ immune-modulatory potency using targeted lipidomic profiling of sphingolipids

doi: 10.1016/j.jcyt.2021.12.009

Figure Lengend Snippet: Unstimulated and IFN-γ–stimulated BM-MSC SL profile. (A) Schematic illustrating IDO converting tryptophan to kynurenine (kyn), an immunosuppressive metabolite. (B) SL concentrations of unstimulated and IFN-γ–primed MSCs. (C) PCA of high and low IDO unstimulated (Unstim) MSC groups. (D) PCA variable plot of MSC groups. (E) PCA of high and low IDO IFN-γ–primed groups. (F) PCA variable plot of IFN-γ groups. (G) LDA of high and low MSCs from Unstim and IFN-γ groups. *Statistical significance (P < .05). Mann–Whitney U test was used to determine significance. All groups were measured in triplicates (n = 3).

Article Snippet: Graphical illustrations of PCA variable loading plots were generated in RStudio.

Techniques: MANN-WHITNEY